Fa'amatalaga o oloa
O le Boswellia Extractt na maua e ala i le suʻeina o le CO₂ sili, faʻaalia:
Tolu Autu Faamanuiaga:
Anti-Mechanism Inflammatory:
Filifilia 5-LOX fa'alavelave (70%↓ leukotriene synthesis)
COX-1/2 fa'asao (leai ni a'afiaga GI e feso'ota'i ma NSAID)
Puipuiga Soofaatasi:
MMP-3/9 fa'alavelave (enzymes e fa'aleagaina le cartilage)
Fa'afoma'i fa'afoma'i fa'aleleia sikoa OA WOMAC ile 40%
Immune Modulation:
Paleni Th1/Th2 cytokines
Fa'aiti'itia TNF- , IL-6 fa'atupu fa'aletonu
Fa'afaigaluega Autu:
Boswellic Acids ( Sili atu pe tutusa ile 65%): AKBA (Acetyl-11-keto- -boswellic acid) e fai ma vaila'au fa'ama'i.
Polysaccharides ( Sili atu pe tutusa ile 15%): Immunomodulatory galuega
Suau'u Taua (5-10%): -Pinene, limonene, ma isi.
Tetracyclic Triterpenes: Vaega o le antitumor
Punavai Botanical: Resin o Boswellia serrata
Meatotino Faaletino: Samasama enaena enaena pauta, manogi lelei, lipid-soluble
Fa'amatalaga:
AKBA anotusi Sili atu pe tutusa ile 10% (maualuga-vaega malosi)
E usita'i i tapulaa uamea mamafa a le USP
Ole aofa'i ole microbial E itiiti ifo pe tutusa ile 1000 CFU/g
A'oa'oga vs Synthetic Anti-a'i fulafula:
✓ Leai se fa'aleagaina o le mucosa gastric
✓ Le faia-se masani
✓ Tele-gaioiga felagolagomai
Su'esu'ega Fa'atekinisi
|
Fa'agasologa |
Fa'afouga Autu |
QC Tulaga |
|
Supercritical CO₂ |
Preserves thermolabile compounds (>95% suauu taua) |
GC-MS suau'u fa'ata'ita'iga |
|
Molecular distillation |
AKBA purity >85% |
HPLC-UV boswellic acid su'ega |
|
Nano-emulsification |
Fa'aleleia le soluble vai (3×↑ bioavailability) |
Fa'apei leisa (D90<200nm) |
|
Microencapsulation |
Puipuia le fa'ama'iina (36-masina mautu) |
ORAC mata'ituina taua |
Tulaga Tauvaga
Fa'amaonia ile falema'i: 28 fa'ata'ita'iga a tagata (e aofia ai le EMA-fa'ailoga OA tulivae)
Fa'amatalaga Saogalemu: GRAS status, LD50 >5000mg/kg (o'ona mata'utia o isumu)
Fuafuaga Synergistic:
60%↑ aoga pe a tuʻufaʻatasia ma curcumin
Fa'atasi ma le Type II collagen mo le soifua maloloina fa'atasi
Tusipasi: ISO22000, USDA/EU Orangic, HACCP, HALAL
Talosaga
① Falema'i
Osteoarthritis: Lagolago -papama'i fa'amalolo (500mg ma le 50mg AKBA)
Lagolago IBD: Enteric-kapisi fa'apipi'i (colon-fa'atatau)
② Mea'ai Tau Ta'aloga
Toe fa'aleleia -fa'amalositino: Fa'atasi ai ma le bromelain (fa'aitiitia le DOMS)
Tausiga sooga: Lamu taifau (fa'atasi ai ma le glucosamine)
③ Mea'ai Fa'atino
Mea inu -tete'e: Turmeric-Boswellia meainu (malulu-faatumu)
Mea'ai a tagata matutua: Malo malō i le taeao-fa'aitiitia cereals
④ Tausiga a le Tagata Lava Ia
Togafitiga o le tino: Anti-C. acnes formulations (pH5.5)
Tausiga o le ulu: Fofo o seborrheic dermatitis (1% salicylic acid)
⑤ Soifua Maloloina o Manu
Equine lagolago soofaatasi: Liposomal tui
Fa'ato'aga: Fa'aopoopo -fa'aola le puipuiga
Tulaga o Maketi
Maketi fa'ama'i fa'ama'i -fa'ato'aga i le lalolagi atoa CAGR 12.4% (2024-2030). Fautuaina atinae:
Fa'atatau i le Tiliva: Fua -maoti nanoparticles (so'oga/gutu)
Tu'ufa'atasiga Fa'afouga: Probiotic fa'apipi'i
Cosmeceuticals: Anti-fa'aata fa'apipi'i transdermal
O lo'o avanoa auaunaga fa'apitoa:
AKBA mataupu (10%-85%)
Suavai
Fa'ata'ita'iga fa'ata'ita'iga lagolago
Fa'aputuina & Teuina
- afifiina: 1kg/pepa pepa pepa, 25kg/fiber pa'u (fa'atonu)
- Teuina: Teu i se nofoaga malulu, matutu, faʻamau ma puipuia mai le malamalama
- Ola Fa'asao: 24 masina (i lalo o tulaga e le'i tatalaina)
Tasi le tautua
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