Fa'amatalaga o oloa
White peony glycosides o se monoterpene glycoside na maua mai i a'a Paeonia lactiflora, ua iloa o le vaega autu o vailaau fa'aSaina masani "White Peony Root" fa'atasi ai ma a'afiaga -fa'amalama, analgesic, ma neuroprotective. Fa'aaogāina -tekonolosi fa'atauva'a-i le taimi nei (HSCCC), e maua ai e le matou oloa se tulaga mata'utia e 99.5% -maualuga le mama ma le 5x fa'asiliina le bioavailability pe a fa'atusatusa i fa'amatalaga masani. Lisi e fai ma fa'amatalaga fa'asino ile Chinese Pharmacopoeia 2020.
Uiga Oloa
|
Parameter |
Fa'amatalaga |
|
Punavai |
A'a mago oPaeonia lactifloraPall. (Ranunculaceae) |
|
Fa'aaliga |
Pa'epa'e ile pa'epa'e-pa'epa'e tioata |
|
Mama |
Sili atu pe tutusa ile 98% (HPLC) |
|
Fuafua mole |
C₂₃H₂₈O₁₁ |
|
Molecular Weight |
480.47 |
|
Solubility |
Solu fua ile methanol/ethanol, solu teisi ile vai (1g/100mL, 25 tikeri) |
|
Tusipasi |
ISO22000, HACCP, USDA Organic, Halal |
Su'esu'ega Fa'ainisinia
|
Vaega |
Anotusi/Metotia |
Faamanuiaga |
|
Paeoniflorin |
Sili atu pe tutusa ile 98% (HPLC-ELSD) |
NF-κB auala fa'alavelave (30% sili atu le aoga nai lo le dexamethasone) |
|
Albiflorin |
E itiiti ifo pe tutusa ile 1.0% |
Synergistically faʻaleleia le GABA receptor gaioioiga (anxiolytic) |
|
Metala mamafa |
Pb Itiiti ifo pe tutusa ile 0.5ppm |
Osi fa'atatau ile ICH Q3D ta'iala ole fa'aleagaina ole elemene |
|
Toega Solvent |
Methanol E itiiti ifo pe tutusa ile 200ppm |
Fa'amalieina mana'oga EP pharmacopeia |
Parameter Autu:
Lisi Lisi: 196-198 tikeri (palapala)
Ta'amilosaga Fa'apitoa: [ ]D²⁰=-12.5 tikeri (c=1, i le methanol)
Ma'imau ile Fa'amago: E itiiti ifo pe tutusa ile 1.0%
Talosaga
▍ Falema'i
Iniseti -Atritis: Tu'ufa'atasi ma le methotrexate (fa'aitiitia oona)
Neuroprotectants: Ischemic stroke IV fa'atulagaina (fa'ata'ita'iga o le Vaega III)
▍ Nutraceuticals
Puipuiga ate: Fa'aitiitia le maualuga o le ALT/AST (40% le fa'aitiitia o su'esu'ega ile falema'i)
Anti-Peletise Gummies: Fa'asa'o vave-(15-minute amata)
▍ mea teuteu
Fa'alelei Pa'u ma'ale'ale: TRPV1 fa'afefe talitali (72%↓ lagona mu)
Anti-Suruma Ma'i Laulu: Fa'alautele le vaega o anagen (35%↑ lauulu mafiafia i vivo)
▍ Fomai Veterinary
Canine Epilepsy Adjunct: Fa'aitiitia le fua ole phenobarbital ile 30%
▍ Su'esu'ega Reagents
TLR4 Pathway Studies: Fuafuaga su'esu'e sela (CAS 23180-57-6)
Fa'aputuina & Teuina
- afifiina: 1kg/pepa pepa pepa, 25kg/fiber pa'u (fa'atonu)
- Teuina: Teu i se nofoaga malulu, matutu, faʻamau ma puipuia mai le malamalama
- Ola Fa'asao: 24 masina (i lalo o tulaga e le'i tatalaina)
Tasi le tautua
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