1. Uiga Fa'asao & Taua Fa'aleaganu'u
Polygonatum (Polygonatum sibiricum poʻo P. kingianum), faʻaaloalogia o le "Herb of Immortality" i Faʻafomai FaʻaSaina (TCM), o loʻo i ai:
Polysaccharides (15-30%): Vaega autu immunomodulatory
Saponins (Kingianosides A-G): Anti-fatigue bioactive compounds
Homoisoflavonoids: Phytoestrogen-pei o tulafono faatonutonu
2. Vaega Autu ma Mechanisms
2.1 Auala -Atua
2.2 Autu Bioactive & Sini
|
Vaega |
Anotusi |
Fa'ainisinia |
Aafiaga Fa'afoma'i |
|
Polysaccharides |
15-30% |
Fa'atonu le ala TLR4/NF-κB |
Fa'aitiitia le matua -fa'atupu fa'alavelave |
|
Kingianoside D |
0.5-1.2% |
Fa'agaoioia le ala malosi AMPK |
Fa'aleleia le fa'amalositino tumau |
|
Polygonatumin A |
0.3-0.8% |
Faʻamalosia le auala antioxidant Nrf2 |
Fa'ateleina le maualuga ole glutathione ile 40% |
3. Tulaga Fa'amaonia Tulaga Lelei
3.1 Fa'amaoni
Uiga fa'akomepiuta: O vaega felavasa'i o lo'o fa'aalia ai fusi vascular concentric
Chromatographic fingerprint: E tatau ona fa'aalia 7 uiga maualuga
DNA fa'ailoga: Fa'amaoniga o ituaiga e ala ile fa'asologa o kenera matK
3.2 Tulaga Fa'aonaponei
Chinese Pharmacopoeia: Polysaccharides Sili atu pe tutusa ile 25%
USP: Aofa'i u'amea mamafa<10ppm
Tulaga a le EU: Toega o vailaau fa'asaina<0.01ppm
4. Fa'amatalaga Fa'afoma'i
4.1 Talosaga Tetee-Atua
Immunosenescence: 1g/aso si'itia le gaioiina o le NK i le 35% i tagata matutua
Fa'aleleia o le mafaufau: MMSE sikoa faʻaleleia ile 3.2 points ile 6 masina
4.2 Lagolago Metabolic
Ma'i suka: Fa'aitiitia le kulukose anapogi ile 1.8mmol/L (CGM-fa'amaonia)
Adrenal vaivai: Fa'asalaina le pa'u cortisol i le 67% o tagata fa'aoga
5. Fa'atonu Fa'aoga Fa'atonu
5.1 Tu'ufa'atasiga Fa'atasi
Faatasi ai ma Ganoderma: Faʻaleleia le immunomodulation
Faʻatasi ai ma Astragalus: A'afiaga Qi -e sili atu
Faatasi ai ma Schisandra: Faʻaleleia le faʻafefeteina o popolega
5.2 Fa'asalaga
Fa'aletonu o le autoimmune: Fa'alavelave fa'afuase'i fa'aletonu e mafai ona puipuia
Estrogen-tulaga ma'ale'ale: Manaomia le fa'aeteete (e iai phytoestrogens)
6. Mea Fa'apitoa Oloa
Fa'ailoga Fa'amaoni:
vao-seleni mai Sichuan/Western Hubei
Ave'esega lua (vai + 30% ethanol)
Su'ega gaioioiga telomerase vaega lona tolu-
Tulaga mulilua:
Fa'afefiloi ma le Disporopsis rhizomes
Polysaccharide fa'afugaga
7. Tu'u -Su'esu'ega
Mitophagy induction: Fa'amama le mitochondria fa'aletonu
Utu -fa'aogaina o le fai'ai: Fa'ateleina le faitau aofa'i o Bifidobacterium
Fa'aoga autu: Fa'aosofia le tu'ufa'atasiga o collagen
Fa'ai'uga Fa'asaienisi
Polygonatum extract e aumaifa'afouina-fa'agaioiga fa'atolu:
1️⃣ Faafouga telefoni(telomere tausiga + mitochondrial turnover)
2️⃣ Paleni fa'aletino(tu'i-metabolic-gaogao fa'agata)
3️⃣ Meleniuma-faamaonia le saogalemu(2000+ tausaga ile TCM)
